IL-11 Protein

Catalog No. ABIN6700008

Supplier Product No.: 009-001-v49-0010

Product Details

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Supplier Product No.: 009-001-v49-0010

Supplier: Rockland

Purpose: Human Interleukin-11 Recombinant Protein

Purification: Interleukin-11 purity was determined to be greater than 95% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.

Purity: 95,00%

Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the dose-dependent proliferation of T11 or TF-1 cells is typically less than 2.5 ng/mL or 10 ng/mL or 4 x 10^5 units/mg or 1 x 10^5 units/mg.

Application Details

Application Notes:

Other: User Optimized

Application_Note: Interleukin-11 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Interleukin-11 in immunological assays.

Comment:

Suggested_Applications: Cellular Assay

Other_Performance_Data:

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 10 μL (10-100 μL)

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Alternative Name: IL11 (IL11 Products)

Background:

Synonyms: AGIF (Adipogenesis Inhibitory Factor), Oprelvekin

Background: Interleukin 11 (IL-11) is a pleotropic cytokine closely related to IL-6 in function, but is overall one of the lesser characterized interleukins. In hematopoietic cell populations, IL-11 is thought to induce megakaryocyte differentiation. In non-hematopoietic populations, IL-11 is thought to be able to stimulate hepatic acute-phase proteins. Human IL-11 can stimulate murine cells. Recombinant human IL-11 is a non-glycosylated protein, containing 179 amino acids, with a molecular weight of 19.3 kDa.

UniProt: P20809

Pathways: JAK-STAT Signaling, Negative Regulation of Hormone Secretion