CXCL3 Protein

Catalog No. ABIN6699700

Supplier Product No.: 009-001-v17-0100

Product Details

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Supplier Product No.: 009-001-v17-0100

Supplier: Rockland

Purpose: Human Gro g / Macrophage Inflammatory Protein-2 beta Recombinant Protein

Purification: Gro g / Macrophage Inflammatory protein-2 beta purity was determined to be greater than 98% as determined by reducing and non-reducing SDS-pAGE.

Purity: 98,00%

Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the ability to chemoattract human neutrophils at concentrations between 10-100 ng/mL.

Application Details

Application Notes:

Other: User Optimized

Application_Note: GRO-gamma Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-GRO-gamma in immunological assays.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.01 M Sodium Phosphate, pH 7.5

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))

Alternative Name: CXCL3 (CXCL3 Products)

Background:

Synonyms: Macrophage inflammatory protein 2-beta (MIP-2β), Growth-regulated protein gamma(GRO-gamma), GRO3

Background: Growth Regulated Proteins (GRO) are a group of three proteins, GRO-α, -β and -g, that are encoded by three distinct genes. All 3 GRO proteins can bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, angiogenesis, and growth regulation. More specifically, GRO gamma (also called CXCL3), can act through chemokine receptor CXCR2 to promote monocyte migration and adhesion. Recombinant human GRO gamma is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 7.9 kDa.

UniProt: P19876

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy