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CXCL10 Protein

Rockland 010-001-v69-0005 CXCL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Rockland
Catalog No. ABIN6699674
Supplier Product No.: 010-001-v69-0005
  • Target See all CXCL10 Proteins
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    Protein Type
    Recombinant
    Origin
    • 15
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 26
    • 5
    • 3
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Supplier Product No.
    010-001-v69-0005
    Supplier
    Rockland
    Purpose
    Mouse IP-10 (CXCL10) Recombinant Protein
    Purification
    Ip-10 (CXCL10) purity was determined to be greater than 97% as determined by HpLC and by reducing and non-reducing SDS-pAGE.
    Purity
    97,00%
    Endotoxin Level
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    The activity is determined by its ability to chemoattract primary human T cells at 0.1-10 ng/mL.
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  • Application Notes

    Other: User Optimized

    Application_Note: IP-10 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-IP-10 in immunological assays.

    Comment

    Suggested_Applications: Cellular Assay

    Other_Performance_Data:

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 5 μL (5-50 μL)

    Buffer

    Buffer: 0.1 % Trifluoroacetic acid

    Stabilizer: None

    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    Expiry Date
    6 months
  • Target
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    Alternative Name
    Cxcl10 (CXCL10 Products)
    Background

    Synonyms: 10 kDa interferon gamma-induced protein (IP-10), C7, Interferon-gamma induced protein CRG-2, small-inducible cytokine B10

    Background: The chemokine IP-10 (or CXCL10) is a chemokine made by monocytes, endothelial cells and fibroblasts in response to treatment with IFNγ. IP-10 functions as a chemoattractant to cells expressing the G protein-coupled receptor, CXCR3, which is found mainly on activated T cells and NK cells. IP-10 plays an important role in Th1 type inflammatory diseases and autoimmune diseases such as, Hashimoto's thyroiditis, Graves' disease and Type 1 diabetes mellitus. Recombinant mouse IP-10 is a non-glycosylated protein, containing 77 amino acids, with a molecular weight of 8.7 kDa.

    UniProt
    P17515
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