NQO1 Protein (AA 1-274) (His tag)
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- Target See all NQO1 Proteins
- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-274
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NQO1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NQO1, 1-274 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NQO1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCL buffer (pH 8.0) containing 10% glycerol 1mM DTT.
- Storage
- 4 °C
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- Target
- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
- Alternative Name
- NQO1 (NQO1 Products)
- Synonyms
- zgc:77191 Protein, wu:fb63c10 Protein, nqo1 Protein, DHQU Protein, DIA4 Protein, DTD Protein, NMOR1 Protein, NMORI Protein, QR1 Protein, Dia4 Protein, AV001255 Protein, Dtd Protein, Nmo-1 Protein, Nmo1 Protein, Nmor1 Protein, Ox-1 Protein, Ox1 Protein, Qr1 Protein, NADPH-d Protein, NAD(P)H dehydrogenase, quinone 1 Protein, NAD(P)H quinone dehydrogenase 1 Protein, NAD(P)H dehydrogenase, quinone 1 L homeolog Protein, nqo1 Protein, NQO1 Protein, Bpet2092 Protein, nqo1.L Protein, Nqo1 Protein
- Background
- NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Recombinant NQO1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DHQU, DIA4, DTD, NMOR1, NMORI, QR1, Azoreductase, Quinone reductase 1, DT-diaphorase, NAD(P)H dehydrogenase, quinone 1, Azoreductase.Menadione reductase, NQO 1, QR 1, Phylloquinone reductase, Cytochrome b 5 reductase, DIA 4, Diaphorase (NADH/NADPH), Diaphorase 4 Dioxin inducible 1, DT diaphorase, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), NAD(P)H dehydrogenase quinone 1 NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I. NCBI no.: NP_000894
- Molecular Weight
- 33.0 kDa (294aa), confirmed by MALDI-TOF.
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