NAT1 Protein (AA 1-290) (His tag)
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- Target See all NAT1 Proteins
- NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-290
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NAT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- NAT1, 1-290aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NAT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))
- Alternative Name
- NAT1 (NAT1 Products)
- Synonyms
- AAC1 Protein, MNAT Protein, NAT-1 Protein, NATI Protein, Nat-1 Protein, Nat Protein, NAT1 Protein, AT-I Protein, N-acetyltransferase 1 Protein, N-acetyl transferase 1 Protein, N-acetyltransferase 1 (arylamine N-acetyltransferase) Protein, arylamine N-acetyltransferase 1-like Protein, NAT1 Protein, Nat1 Protein, LOC101095575 Protein
- Background
- NAT1 belongs to the arylamine N-acetyltransferase family. It catalyzes N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high levels of N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NAT1 also bioactivate several known carcinogens. This enzyme helps metabolize drugs and other xenobiotics, and participates in the detoxification of a plethora of hydrazine and arylamine drugs. Recombinant human NAT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Arylamine N-acetyltransferase 1, AAC1, MNAT, NAT-1, NATI. NCBI no.: NP_001153644
- Molecular Weight
- 36.1 kDa (310aa), confirmed by MALDI-TOF
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