Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) (AA 1-228) protein (His tag)
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- Target See all Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1) Proteins
- Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-228
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Application
- SDS-PAGE (SDS)
- Characteristics
- CMPK1, 1-228aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CMPK1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl
- Storage
- 4 °C
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- Target
- Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
- Alternative Name
- CMPK1 (CMPK1 Products)
- Synonyms
- CK Protein, CMK Protein, CMPK Protein, UMK Protein, UMP-CMPK Protein, UMPK Protein, UMP/CMPK Protein, PSPTO1749 Protein, cmpk1 Protein, fb52d08 Protein, fk47a07 Protein, ump Protein, wu:fb52d08 Protein, wu:fk47a07 Protein, zgc:56452 Protein, Cmpk Protein, RGD1310116 Protein, cmpk Protein, 0610011D08Rik Protein, UMP-CMPk Protein, UCK Protein, cytidine/uridine monophosphate kinase 1 Protein, cytidylate kinase Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic Protein, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic S homeolog Protein, cytidylate kinase Cmk Protein, cytidine monophosphate (UMP-CMP) kinase 1 Protein, CMPK1 Protein, cmk Protein, cmpk1 Protein, cmpk Protein, Cmpk1 Protein, cmpk1.S Protein, Mrub_0478 Protein, MMAH_RS06670 Protein, TAGG_RS04320 Protein, Trad_0784 Protein, Deba_2713 Protein, Toce_1154 Protein, VDIS_RS03585 Protein, Fbal_1939 Protein, Ilyop_1379 Protein, Lbys_3481 Protein, Calni_0093 Protein, Ftrac_1556 Protein, Ocepr_1777 Protein
- Background
- CMPK1, also known as UMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: UMP-CMP kinase, CMK, CMPK, RP11-511I2.1, UMK, UMP-CMPK, UMPK. NCBI no.: NP_057392
- Molecular Weight
- 28.0 kDa (248aa), confirmed by MALDI-TOF
- Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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