COMMD1 Protein (AA 1-190) (His tag)
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- Target See all COMMD1 Proteins
- COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-190
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This COMMD1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- COMMD1, 1-190aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product COMMD1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl
- Storage
- 4 °C
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- Target
- COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
- Alternative Name
- COMMD1 (COMMD1 Products)
- Synonyms
- C2orf5 Protein, MURR1 Protein, murr1 Protein, commd1 Protein, si:ch211-213b8.2 Protein, DDBDRAFT_0184206 Protein, DDBDRAFT_0266452 Protein, DDB_0184206 Protein, DDB_0266452 Protein, COMMD1 Protein, MGC114682 Protein, AI256843 Protein, Murr1 Protein, U2/Mu Protein, copper metabolism domain containing 1 Protein, copper metabolism (Murr1) domain containing 1 Protein, COMM domain-containing protein 1 Protein, copper metabolism domain containing 1 L homeolog Protein, COMM domain containing 1 Protein, COMMD1 Protein, commd1 Protein, comd1 Protein, Commd1 Protein, commd1.L Protein
- Background
- COMMD1, also known as copper metabolism MURR1 domain-containing protein 1, is a 190 amino acid protein responsible for inhibition of TNF-induced NFkB p50 and has a suggested role in facilitation of biliary copper excretion within hepatocytes. High expression is found in liver tissue, with lower expressions in lung, heart, kidney and brain tissue. This protein interacts directly with COMMD6 and ATP7B, and indirectly with IkB-beta and COMMD7. Recombinant human COMMD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C2orf5, MURR1, COMM domain-containing protein 1, COMMD-1, COMMD 1, COMM, MURR 1, MURR-1. NCBI no.: NP_689729
- Molecular Weight
- 23.3 kDa (210aa), confirmed by MALDI-TOF
- Pathways
- Transition Metal Ion Homeostasis
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