PINK1 Protein (AA 156-507)
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- Target See all PINK1 Proteins
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 156-507
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- PINK1, 156-507 aa , Human, E.coli
- Purity
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) 1M Urea, 5% Glycerol.
- Storage
- 4 °C
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- Target
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
- Alternative Name
- PINK1 (PINK1 Products)
- Background
- PINK1 is a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this protein cause one form of autosomal recessive early-onset Parkinson disease. Recombinant human PINK protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Serine/threonine-protein kinase PINK1, mitochondrial, BRPK, FLJ27236, PARK6. NCBI no.: NP_115785
- Molecular Weight
- 37.9 kDa (353aa)
- Pathways
- Autophagy
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