SGK1 Protein (AA 60-431) (His tag)
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- Target See all SGK1 Proteins
- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 60-431
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SGK1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SGK1, 60-431 aa, Human, His tag, HI-5
- Purity
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.2M NaCl,2mM DTT,0.1mM PMSF
- Storage
- 4 °C
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- Target
- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
- Alternative Name
- SGK1 (SGK1 Products)
- Synonyms
- SGK Protein, Sgk Protein, sgk-B Protein, sgk2 Protein, cb1083 Protein, sgk Protein, wu:fc20a09 Protein, sgk-A Protein, sgk1 Protein, sgk1-a Protein, sgk1-b Protein, serum/glucocorticoid regulated kinase 1 Protein, Serine/threonine-protein kinase sgk-1 Protein, serum/glucocorticoid regulated kinase 1 S homeolog Protein, serum/glucocorticoid regulated kinase 1 L homeolog Protein, SGK1 Protein, Sgk1 Protein, sgk-1 Protein, sgk1.S Protein, sgk1 Protein, sgk1.L Protein
- Background
- SGK1, also known as serum-and glucocorticoid-regulated kinase, is a serine/threonine protein kinase and a member of the “AGC” subfamily, which includes protein kinases A, G, and C. This protein plays an important role in activating certain potassium, sodium and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. It is activated in vitroby 3-phosphoinositide-dependent protein kinase-1 (PDK-1) and in vivoin response to signals that activate phosphatidylinositol (PI) 3-kinase. Recombinant human SGK1 protein was expressed with N-terminal His-tag in High-Five cells using baculovirus expression system and purified by using conventional chromatography techniques. Synonyms: Serine/threonine-protein kinase Sgk1 isoform 1,. NCBI no.: NP_005618
- Molecular Weight
- 44.5 kDa (393aa)
- Pathways
- MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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