RGS10 Protein (AA 1-181) (His tag)
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- Target See all RGS10 Proteins
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-181
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RGS10 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RGS10, 1-181aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RGS10 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
- Alternative Name
- RGS10 (RGS10 Products)
- Synonyms
- MGC82511 Protein, RGS10 Protein, 2310010N19Rik Protein, regulator of G-protein signaling 10 Protein, regulator of G-protein signaling 10 L homeolog Protein, regulator of G protein signaling 10 Protein, regulator of G-protein signalling 10 Protein, RGS10 Protein, rgs10.L Protein, rgs10 Protein, Rgs10 Protein
- Background
- Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10(RGS10) belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. RGS10 protein is localized in the nucleus. Recombinant human RGS10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Regulator of G-protein signaling 10, Regulator of G protein signaling 10. NCBI no.: NP_001005339
- Molecular Weight
- 23.7 kDa (205aa), confirmed by MALDI-TOF
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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