UBE2D1 Protein (AA 1-147) (His tag)
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- Target See all UBE2D1 Proteins
- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-147
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2D1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- UBE2D1, 1-147aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product UBE2D1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
- Alternative Name
- UBE2D1 (UBE2D1 Products)
- Synonyms
- E2(17)KB1 Protein, SFT Protein, UBC4/5 Protein, UBCH5 Protein, UBCH5A Protein, ube2d1 Protein, wu:fc16h06 Protein, zgc:73096 Protein, e2(17)kb1 Protein, sft Protein, ubc4/5 Protein, ubch5 Protein, ubch5a Protein, ubiquitin conjugating enzyme E2 D1 Protein, ubiquitin-conjugating enzyme E2D 1 Protein, ubiquitin-conjugating enzyme E2D 1b Protein, ubiquitin conjugating enzyme E2 D1 S homeolog Protein, UBE2D1 Protein, Ube2d1 Protein, ube2d1b Protein, ube2d1.S Protein, ube2d1 Protein
- Background
- UBE2D1 belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2D1 is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Recombinant human UBE2D1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Ubiquitin-conjugating enzyme E2D 1, SFT, UBC5A, UBCH5, UBCH5A. NCBI no.: NP_003329
- Molecular Weight
- 19.0 kDa (170aa), confirmed by MALDI-TOF
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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