EEF1E1 Protein (AA 1-174) (His tag)
-
- Target See all EEF1E1 Proteins
- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-174
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EEF1E1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- EEF1E1, 1-174aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product EEF1E1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
- Storage
- 4 °C
-
- Target
- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
- Alternative Name
- EEF1E1 (EEF1E1 Products)
- Synonyms
- p18 Protein, AIMP3 Protein, P18 Protein, 1110003A02Rik Protein, eukaryotic translation elongation factor 1 epsilon 1 Protein, eukaryotic translation elongation factor 1 epsilon 1 L homeolog Protein, EEF1E1 Protein, eef1e1.L Protein, eef1e1 Protein, Eef1e1 Protein
- Background
- EEF1E1, also known as, eukaryotic translation elongation factor 1 epsilon-1, shares sequence similarity with the amino-terminal ends of the Beta and Gamma subunits of EF-1. By specifically interacting with MetRS, this protein binds to a macromolecular tRNA synthtase complex that catalyzes the ligation of specific amino acids to their cognate tRNAs. Upon DNA damage, it translocates to the nucleus where it interacts with ATM and ATR, resulting in p53 activation. Recombinant human EEIF1E1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Eukaryotic translation elongation factor 1 epsilon-1, AIMP3, P18. NCBI no.: NP_004271
- Molecular Weight
- 21.9 kDa (194aa) confirmed by MALDI-TOF
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
-