MMAB Protein (AA 33-250) (His tag)
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- Target See all MMAB Proteins
- MMAB (Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-250
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MMAB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- MMAB, 33-250aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product MMAB Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 10% Glycerol
- Storage
- 4 °C
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- Target
- MMAB (Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB))
- Alternative Name
- MMAB (MMAB Products)
- Synonyms
- ATR Protein, cblB Protein, cob Protein, 9130222L19Rik Protein, methylmalonic aciduria (cobalamin deficiency) cblB type Protein, methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) Protein, MMAB Protein, Mmab Protein
- Background
- MMAB is a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12 containing coenzyme for methylmalonyl-CoA mutase(MCM). Impaired MMAB activity leads to the inherited disorder vitamin B12 dependent methylmalonic aciduria linked to the cblB complementation group. Recombinant human MMAB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: ATR, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type. NCBI no.: AAH05054
- Molecular Weight
- 26.3 kDa(239aa), confirmed by MALDI-TOF
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