BIN1 Protein (AA 1-439) (His tag)
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- Target See all BIN1 Proteins
- BIN1 (Bridging Integrator 1 (BIN1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-439
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BIN1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BIN1, 1-439aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS – PAGE
- Top Product
- Discover our top product BIN1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- BIN1 (Bridging Integrator 1 (BIN1))
- Alternative Name
- BIN1 (BIN1 Products)
- Synonyms
- bin1 Protein, MGC53185 Protein, amph2 Protein, amphl Protein, sh3p9 Protein, MGC76187 Protein, cb57 Protein, zgc:86701 Protein, BIN1 Protein, AMPH2 Protein, AMPHL Protein, SH3P9 Protein, ALP-1 Protein, Amphl Protein, BRAMP-2 Protein, bridging integrator 1 Protein, bridging integrator 1 S homeolog Protein, bridging integrator 1b Protein, BIN1 Protein, bin1.S Protein, bin1 Protein, bin1b Protein, Bin1 Protein
- Background
- BIN1, also known as SH3P9, is a nucleocytoplasmic adaptor protein, one of which was initially identified as MYC-interacting protein with features of a tumor suppressor. This protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers. The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver. Recombinant human BIN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AMPH2, AMPHL, MGC10367, SH3P9, Amphiphysin II, Myc box-dependent-interacting protein 1. NCBI no.: AAH04101
- Molecular Weight
- 50.4 kDa (459aa) confirmed by MALDI-TOF
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