OGG1 Protein (AA 1-345) (His tag)
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- Target See all OGG1 Proteins
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-345
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This OGG1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- OGG1, 1-345aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product OGG1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) Containing 100 mM NaCl, 40% Glycerol
- Storage
- 4 °C
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- Target
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- Alternative Name
- OGG1 (OGG1 Products)
- Synonyms
- OGG1 Protein, zgc:158858 Protein, 8-oxoguanine-DNA glycosylase 1 Protein, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 Protein, ATOGG1 Protein, F8K7.14 Protein, F8K7_14 Protein, 19.m02329 Protein, DDBDRAFT_0184479 Protein, DDBDRAFT_0233024 Protein, DDB_0184479 Protein, DDB_0233024 Protein, ogg1 Protein, Tb04.1H19.930 Protein, HMMH Protein, HOGG1 Protein, MUTM Protein, OGH1 Protein, Mmh Protein, 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA glycosylase L homeolog Protein, 8-oxoguanine-DNA glycosylase 1 Protein, 8-OXOGUANINE DNA GLYCOSYLASE Protein, putative 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA-glycosylase Protein, N-glycosylase/DNA lyase OGG1 Protein, 8-oxoguanine DNA-glycosylase 1 Protein, OGG1 Protein, ogg1.L Protein, ogg1 Protein, ECU08_0770 Protein, CA_C2707 Protein, BBOV_I004290 Protein, Smp_074010.1 Protein, LOC9329243 Protein, Tb927.4.2480 Protein, Ogg1 Protein
- Background
- OGG1, also known as 8-oxoguanine glycosylase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS). It has a beta lyase activity that nicks DNA 3' to the lesion. Recombinant human OGG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: HMMH, HOGG1, MUTM, OGH1, AP lyase, 8-oxoguanine DNA glycosylase 1. NCBI no.: AAH00657
- Molecular Weight
- 41.2 kDa(368aa), confirmed by MALDI-TOF
- Pathways
- DNA Damage Repair
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