Fascin Protein (FSCN1) (AA 1-493) (His tag)
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- Target See all Fascin (FSCN1) Proteins
- Fascin (FSCN1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-493
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Fascin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- FSCN1, 1-493aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product FSCN1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl
- Storage
- 4 °C
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- Target
- Fascin (FSCN1)
- Alternative Name
- FSCN1 (FSCN1 Products)
- Synonyms
- CG15331 Protein, CG1536 Protein, CG32858 Protein, Dmel\\CG32858 Protein, SN Protein, Sn Protein, fs(1)A1057 Protein, fs(1)K1421 Protein, fs(1)K418 Protein, fs(1)K473 Protein, fs(1)K743 Protein, fs(1)M45 Protein, p55 Protein, snl Protein, MGC75811 Protein, fscn1 Protein, sb:cb589 Protein, zgc:153632 Protein, AI663989 Protein, Fan1 Protein, fascin-1 Protein, Fascin Protein, fscn Protein, FAN1 Protein, HSN Protein, SNL Protein, fascin Protein, singed Protein, fascin actin-bundling protein 1 Protein, fascin actin-bundling protein 1a Protein, fascin actin-bundling protein 1 L homeolog Protein, sn Protein, fscn1 Protein, fscn1a Protein, Fscn1 Protein, fscn1.L Protein, FSCN1 Protein
- Background
- FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells. Recombinant human FSCN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: FAN1, HSN, SNL, Fascin. NCBI no.: NP_003079
- Molecular Weight
- 56.7kDa (513aa)
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