RUNX3 Protein (AA 53-186) (His tag)
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- Target See all RUNX3 Proteins
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 53-186
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RUNX3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RUNX3, 53-186aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product RUNX3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT
- Storage
- 4 °C
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- Target
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
- Alternative Name
- RUNX3 (RUNX3 Products)
- Synonyms
- runxb Protein, RUNX3 Protein, CBFA3 Protein, frrunx3 Protein, runx3 Protein, aml2 Protein, cbfa3 Protein, pebp2ac Protein, AML2 Protein, Cbfa3 Protein, Pebp2a3 Protein, PEBP2aC Protein, runt-related transcription factor 3 Protein, runt related transcription factor 3 Protein, runt related transcription factor 3 L homeolog Protein, runx3 Protein, RUNX3 Protein, runx3.L Protein, Runx3 Protein
- Background
- RUNX3, also known as runt-related transcription factor 3, belongs to the RUNX family that regulate the expression of genes involved in cellular differentiation and cell cycle progression. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It is a strong candidate as a gastric cancer tumor suppressor. Recombinant human RUNX3, fused to His-tag at N-terminus, protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RUNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2. NCBI no.: NP_004341
- Molecular Weight
- 17.1 kDa (155aa) confirmed by MALDI-TOF
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