WWOX Protein (AA 1-234) (His tag)
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- Target See all WWOX Proteins
- WWOX (WW Domain Containing Oxidoreductase (WWOX))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-234
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WWOX protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- WWOX, 1-234 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product WWOX Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- WWOX (WW Domain Containing Oxidoreductase (WWOX))
- Alternative Name
- WWOX (WWOX Products)
- Synonyms
- CG7221 Protein, DmWWOX Protein, Dmel\\CG7221 Protein, anon-EST:Posey177 Protein, GB11795 Protein, WWOX Protein, D16S432E Protein, FOR Protein, FRA16D Protein, HHCMA56 Protein, PRO0128 Protein, SDR41C1 Protein, WOX1 Protein, zgc:55975 Protein, 5330426P09Rik Protein, 9030416C10Rik Protein, WW domain containing oxidoreductase Protein, WW domain-containing oxidoreductase Protein, Wwox Protein, LOC411815 Protein, WWOX Protein, CpipJ_CPIJ004939 Protein, MCYG_01584 Protein, VDBG_05631 Protein, VDBG_01326 Protein, VDBG_06753 Protein, Tsp_03967 Protein, LOC100284583 Protein, wwox Protein
- Background
- WWOX, also known as WW domain containing oxidoreductase, is a proapoptotic protein and a tumor suppressor protein. WWOX is found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This protein may function synergistically with TP53/p53 to control genotoxic stress-induced cell death. It also plays a role in tumor necrosis factor (TNF)-mediated cell death. Recombinant human WWOX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: WW domain containing oxidoreductase, D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1 , WW domain containing oxidoreductase 5330426P09Rik, 9030416C10Rik, EC 1.1.1.- Fragile site FRA16D Oxireductase, MGC55975, PRO0128, Putative oxidoreductase, zgc:55975, Short chain dehydrogenase/reductase family 41C, member 1, WW domain-containing protein WWOX. NCBI no.: AAH03184
- Molecular Weight
- 28.3 kDa (254aa), confirmed by MALDI-TOF.
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