Survivin Protein (AA 1-142) (Calmodulin (CaM))

Catalog No. ABIN667066

Product Details

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Protein Type: Recombinant

Protein Characteristics: AA 1-142

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Survivin protein is labelled with Calmodulin (CaM).

Application: SDS-PAGE (SDS)

Characteristics: Survivin, AA 1-142, Human, CaM-tagged, Recombinant, E. coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5, 0.1M NaCl.

Storage: 4 °C

Target Details

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: Survivin (BIRC5 Products)

Synonyms: AP14 Protein, API4 Protein, EPR-1 Protein, AAC-11 Protein, Api4 Protein, TIAP Protein, survivin40 Protein, bir5a Protein, survivin Protein, BIR1 Protein, Su2 Protein, XBIR1 Protein, XSurvivin1 Protein, Xsvv1 Protein, api4 Protein, bir1-A Protein, epr-1 Protein, svv1 Protein, xSurvivin Protein, xsurv Protein, Su1 Protein, birc5.2 Protein, svv2 Protein, xSurvivin2 Protein, bir5b Protein, SIX Protein, birc5.2-a Protein, birc5.2-b Protein, baculoviral IAP repeat containing 5 Protein, baculoviral IAP repeat-containing 5 Protein, baculoviral IAP repeat containing 5a Protein, baculoviral IAP repeat-containing 5, gene 1 L homeolog Protein, baculoviral IAP repeat containing 5 L homeolog Protein, baculoviral IAP repeat containing 5b Protein, baculoviral IAP repeat containing 5 S homeolog Protein, BIRC5 Protein, Birc5 Protein, birc5a Protein, birc5.1.L Protein, birc5.2.L Protein, birc5b Protein, birc5.2.S Protein

Background: Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP). The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death. Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E. coli and purified by conventional chromatography techniques. Synonyms: BIRC5, Baculoviral IAP repeat-containing 5, API4, EPR-1, Baculoviral IAP repeat-containing protein 5 isoform 1, Survivin, Baculoviral IAP repeat-containing protein 5 isoform 1 API4, Apoptosis Inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, BIRC 5, EPR 1, IAP4, SVV, TIAP. NCBI no. : AAH34148

Molecular Weight: 33 kDa (294 aa), confirmed by MALDI-TOF.

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding