Survivin Protein (AA 1-142) (Calmodulin (CaM))

Catalog No. ABIN667066

Product Details

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Protein Type: Recombinant

Protein Characteristics: AA 1-142

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Survivin protein is labelled with Calmodulin (CaM).

Application: SDS-PAGE (SDS)

Characteristics: Survivin, AA 1-142, Human, CaM-tagged, Recombinant, E. coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5, 0.1M NaCl.

Storage: 4 °C

Target Details

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: Survivin (BIRC5 Products)

Background: Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP). The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death. Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E. coli and purified by conventional chromatography techniques. Synonyms: BIRC5, Baculoviral IAP repeat-containing 5, API4, EPR-1, Baculoviral IAP repeat-containing protein 5 isoform 1, Survivin, Baculoviral IAP repeat-containing protein 5 isoform 1 API4, Apoptosis Inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, BIRC 5, EPR 1, IAP4, SVV, TIAP. NCBI no. : AAH34148

Molecular Weight: 33 kDa (294 aa), confirmed by MALDI-TOF.

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding