RAB27A Protein (AA 1-221) (His tag)
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- Target See all RAB27A Proteins
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-221
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAB27A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- RAB27A, 1-221aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RAB27A Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
- Alternative Name
- RAB27A (RAB27A Products)
- Synonyms
- MGC80943 Protein, RAB27A Protein, gs2 Protein, ram Protein, rab27 Protein, MGC89827 Protein, hst18676 Protein, zgc:114135 Protein, GS2 Protein, HsT18676 Protein, RAB27 Protein, RAM Protein, 2210402C08Rik Protein, 2410003M20Rik Protein, 4933437C11Rik Protein, ash Protein, RAB27A, member RAS oncogene family L homeolog Protein, RAB27A, member RAS oncogene family Protein, RAB27A, member RAS oncogene family S homeolog Protein, rab27a.L Protein, RAB27A Protein, rab27a Protein, rab27a.S Protein, Rab27a Protein
- Background
- Ras-related protein Rab-27A, also known as RAB27A, belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Also, RAB27A regulates the cytotoxic granule exocytosis and affect T-lymphocyte and macrophage-activation. It is widely expressed with significant expression in pancreatic islets and pituitary tissue, and low expression in brain. Defects in RAB27A cause Griscelli syndrome type 2 (GS2). Recombinant human RAB27A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GS2, RAM, RAB27, Ras-related protein Rab-27A GTP-binding protein Ram, HsT18676.MGC117246, Rab-27, RAB27A, member RAS oncogene family, Ras-related protein Rab27A. NCBI no.: NP_899059
- Molecular Weight
- 27 kDa (241aa), confirmed by MALDI-TOF
- Pathways
- Peptide Hormone Metabolism
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