IVD Protein (AA 33-426) (His tag)
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- Target See all IVD Proteins
- IVD (Isovaleryl-CoA Dehydrogenase (IVD))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-426
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IVD protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- IVD, 33-426aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- IVD (Isovaleryl-CoA Dehydrogenase (IVD))
- Alternative Name
- IVD (IVD Products)
- Synonyms
- 1300016K07Rik Protein, 6720455E18Rik Protein, AI463340 Protein, ACAD2 Protein, ATIVD Protein, ISOVALERYL-COA-DEHYDROGENASE Protein, ISOVALERYL-COA-DEHYDROGENASE PRECURSOR Protein, IVDH Protein, isovaleryl-CoA-dehydrogenase Protein, isovaleryl coenzyme A dehydrogenase Protein, isovaleryl-CoA dehydrogenase Protein, isovaleryl-CoA-dehydrogenase Protein, Ivd Protein, IVD Protein
- Background
- IVD (Isovaleryl Coenzyme A dehydrogenase) is a mitochondrial matrix enzyme that belongs to the acyl-CoA dehydrogenase family. IVD is a homotetrameric flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects of the IVD gene lead to ineffective isoforms that are the underlying cause of isovaleric acidemia. Recombinant human IVD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ACAD2, Isovaleryl-CoA dehydrogenase, mitochondrial Isovaleryl CoA dehydrogenase, Isovaleryl CoA dehydrogenase, mitochondrial, isovaleryl Coenzyme A dehydrogenase. NCBI no.: NP_002216
- Molecular Weight
- 45.3 kDa (415aa), confirmed by MALDI-TOF.
- Pathways
- Monocarboxylic Acid Catabolic Process
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