APRT Protein (AA 1-180)
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- Target See all APRT Proteins
- APRT (Adenine Phosphoribosyltransferase (APRT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-180
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- APRT, 1-180aa, Human, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product APRT Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- APRT (Adenine Phosphoribosyltransferase (APRT))
- Alternative Name
- APRT (APRT Products)
- Synonyms
- Tb07.43M14.200 Protein, Tb07.43M14.180 Protein, C85684 Protein, AMP Protein, APRTD Protein, adenine phosphoribosyltransferase Protein, adenine phosphoribosyl transferase Protein, CND05020 Protein, Tb927.7.1790 Protein, Tb927.7.1780 Protein, Arnit_0941 Protein, Saut_1231 Protein, Fbal_1180 Protein, PH_RS07970 Protein, PF_RS08760 Protein, PAB_RS02560 Protein, Aprt Protein, APRT Protein
- Background
- APRT (adenine phosphoribosyltransferase) is a 180 amino acid protein that localizes to the cytoplasm and belongs to the purine/pyrimidine phosphoribosyltransferase family. Existing as a homodimer, APRT functions to catalyze the formation of inorganic pyrophosphate and AMP from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP), a reaction that is essential for both purine metabolism and AMP biosynthesis. It also produces adenine as a by-product of the polyamine biosynthesis pathway. Recombinant human APRT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AMP, Adenine phosphoribosyltransferase AMP diphosphorylase, AMP pyrophosphorylase, DKFZp686D13177, MGC125856, MGC125857, MGC129961, Transphosphoribosidase. NCBI no.: NP_000476
- Molecular Weight
- 19.6 kDa (180aa), confirmed by MALDI-TOF.
- Pathways
- Ribonucleoside Biosynthetic Process
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