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OAT Protein (AA 33-439)

OAT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN666933
  • Target See all OAT Proteins
    OAT (Ornithine Aminotransferase (OAT))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 33-439
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Characteristics
    OAT, 33-439aa, Human, E.coli
    Purity
    > 90 % by SDS - PAGE
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
    Storage
    4 °C
  • Target
    OAT (Ornithine Aminotransferase (OAT))
    Alternative Name
    OAT (OAT Products)
    Background
    OAT, also known as mitochondrial enzyme ornithine aminotransferase, is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. ( L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.) Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Recombinant OAT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DKFZp781A11155, HOGA, OATASE, ornithine aminotransferase precursor EC 2.6.1.13, ornithine aminotransferase (gyrate atrophy), ornithine aminotransferase precursor, Ornithine aminotransferase, mitochondrial precursor, Ornithine oxo-acid aminotransferase, Ornithine--oxo-acid aminotransferase. NCBI no.: NP_000265
    Molecular Weight
    45.2 kDa (408aa), confirmed by MALDI-TOF.
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