OAT Protein (AA 33-439)
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- Target See all OAT Proteins
- OAT (Ornithine Aminotransferase (OAT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-439
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Characteristics
- OAT, 33-439aa, Human, E.coli
- Purity
- > 90 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
- Storage
- 4 °C
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- Target
- OAT (Ornithine Aminotransferase (OAT))
- Alternative Name
- OAT (OAT Products)
- Background
- OAT, also known as mitochondrial enzyme ornithine aminotransferase, is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. ( L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.) Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Recombinant OAT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DKFZp781A11155, HOGA, OATASE, ornithine aminotransferase precursor EC 2.6.1.13, ornithine aminotransferase (gyrate atrophy), ornithine aminotransferase precursor, Ornithine aminotransferase, mitochondrial precursor, Ornithine oxo-acid aminotransferase, Ornithine--oxo-acid aminotransferase. NCBI no.: NP_000265
- Molecular Weight
- 45.2 kDa (408aa), confirmed by MALDI-TOF.
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