PTS Protein (His tag)
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- Target See all PTS Proteins
- PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTS protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PTS, 1-145aa Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PTS Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))
- Alternative Name
- PTS (PTS Products)
- Synonyms
- PTS Protein, Pts Protein, DDBDRAFT_0232952 Protein, DDB_0232952 Protein, ptps Protein, zgc:162276 Protein, PTPS Protein, 6-pyruvoyltetrahydropterin synthase Protein, 6-pyruvoyltetrahydropterin synthase L homeolog Protein, 6-pyruvoyl-tetrahydropterin synthase Protein, PTS Protein, pts.L Protein, Pts Protein, azo3118 Protein, Xfasm12_0164 Protein, HUTA_RS09790 Protein, Cyan8802_3683 Protein, ptsA Protein, NMAG_RS16995 Protein, pts Protein, DICPUDRAFT_151723 Protein
- Background
- 6-Pyruvoyltetrahydropterin synthase (PTS), also known as PTPS, belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. Recombinant human PTS, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PTPS, PTP synthase, 6-pyruvoyltetrahydropterin synthase 6 pyruvoyl tetrahydrobiopterin synthase, 6 pyruvoyl tetrahydropterin synthase, 6 pyruvoyltetrahydropterin synthase, EC 4.2.3.12, FLJ97081,. NCBI no.: NP_000308
- Molecular Weight
- 18.5 kDa (165aa), confirmed by MALDI-TOF.
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