PSMA7 Protein (AA 1-248) (His tag)
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- Target See all PSMA7 Proteins
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-248
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSMA7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PSMA7, 1-248aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PSMA7 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
- Alternative Name
- PSMA7 (PSMA7 Products)
- Synonyms
- C6 Protein, HSPC Protein, RC6-1 Protein, XAPC7 Protein, C6-I Protein, DDBDRAFT_0185059 Protein, DDBDRAFT_0217080 Protein, DDB_0185059 Protein, DDB_0217080 Protein, hspc Protein, rc6-1 Protein, xapc7 Protein, psma7 Protein, psma4-B Protein, proteasome subunit alpha 7 Protein, proteasome (prosome, macropain) subunit, alpha type 7 Protein, 20S proteasome subunit alpha-7 Protein, proteasome subunit alpha 7 S homeolog Protein, proteasome subunit alpha 7 L homeolog Protein, PSMA7 Protein, Psma7 Protein, psmA7 Protein, psma7 Protein, psma7.S Protein, psma7.L Protein
- Background
- Proteasome alpha 7, PSMA7, is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. PSMA7, belonged to the peptidase T1A family, is a 20S core alpha subunit of proteasome. This protein was found to interact specifically with two subdomains of HIF-1alpha and inhibited the transactivation function of HIF-1alpha under both normoxic and hypoxia-mimicking conditions. Recombinant PSMA7 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C6, HSPC, MGC3755, RC6-1, XAPC7, Proteasome alpha 7 subunit, PSMA7 , Proteasome alpha 7 subunit Proteasome (prosome macropain) subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, PSMA 7, RC6 1, Proteasome subunit RC6 1, Proteasome subunit XAPC7. NCBI no.: NP_002783
- Molecular Weight
- 30.0 kDa (268 aa), confirmed by MALDI-TOF.
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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