Retinoid X Receptor gamma Protein (AA 111-228)

Catalog No. ABIN666801

Product Details

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Protein Type: Recombinant

Protein Characteristics: AA 111-228

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Characteristics: RXR-alpha( Retinoid x receptor, 111-228aa, Human) Recombinant, expressed in E.coli)

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol

Storage: 4 °C

Target Details

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Alternative Name: RXR-alpha (Retinoid X Receptor) (RXRG Products)

Synonyms: NR2B3 Protein, RXRC Protein, zgc:92183 Protein, RXRgamma Protein, RXRG Protein, RXR-gamma Protein, nr2b3 Protein, xrxrg Protein, rxrc Protein, Nr2b3 Protein, NR2B1 Protein, RXR Protein, rxra Protein, rxrg Protein, retinoid X receptor gamma Protein, retinoid X receptor, gamma b Protein, retinoid X receptor gamma L homeolog Protein, retinoid x receptor, gamma a Protein, RXRG Protein, rxrgb Protein, rxrg.L Protein, rxrg Protein, Rxrg Protein, RXRGAMMA Protein, rxrga Protein

Background: The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms, RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques. Synonyms: RXRA, NR2B1, RXR-alpha, Retinoid x receptor, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, FLJ16020, FLJ16733, MGC102720, Retinoic acid receptor RXR alpha, RXR alpha1, RXRalpha1, RXRA1. NCBI no.: NP_002948

Molecular Weight: 13.6 kDa (119 aa), confirmed by MALDI-TOF.

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway