CXCL12 Protein (AA 22-93) (His tag)

Catalog No. ABIN666769

Product Details

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Protein Type: Recombinant

Protein Characteristics: AA 22-93

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CXCL12 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SDF-1 , 22-93aa, Human, His-tagged, Recombinant, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage: 4 °C

Target Details

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Alternative Name: SDF-1 (CXCL12 Products)

Synonyms: IRH Protein, PBSF Protein, SCYB12 Protein, SDF1 Protein, TLSF Protein, TPAR1 Protein, CINC-1 Protein, Gro1 Protein, Pbsf Protein, Scyb12 Protein, Sdf1 Protein, Tlsf Protein, Tpar1 Protein, Fsp Protein, KC Protein, Mgsa Protein, N51 Protein, Scyb1 Protein, gro Protein, sdf-1 Protein, sdf1 Protein, xSDF-1 Protein, SDF-1 Protein, cxcl12 Protein, sdf-1a Protein, sdf1a Protein, wu:fa55e10 Protein, wu:fc16h12 Protein, wu:fj84c02 Protein, C-X-C motif chemokine ligand 12 Protein, C-X-C motif chemokine ligand 1 Protein, chemokine (C-X-C motif) ligand 12 Protein, chemokine (C-X-C motif) ligand 1 Protein, C-X-C motif chemokine ligand 12 L homeolog Protein, chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) Protein, CXCL12 Protein, cxcl12 Protein, Cxcl1 Protein, Cxcl12 Protein, cxcl12.L Protein, cxcl12a Protein

Background: SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes and works by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma. Recombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: SDF-1, Stromal cell-derived factor 1, CXCL12, PBSF, hIRH, Stromal cell-derived factor 1 C-X-C motif chemokine 12, OTTHUMP00000019491, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1, AI174028, Chemokine (C-X-C motif) ligand 12, Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1), Intercrine reduced in hepatomas IRH, Chemokine CXC motif ligand 12, SDF1A, SDF1B, Pre-B cell growth-stimulating factor, SCYB12, SDF 1, Stromal cell-derived factor 1 delta, SDF-1a, SDF-1b, Stromal cell-derived factor 1 gamma, Stromal cell-derived factor 1a, Stromal cell-derived factor-1 alpha, Thymic lymphoma cell-stimulating factor, Tlsf, TLSF-a, TLSF-b, Tlsfa, Tlsfb, TPAR1. NCBI no.: NP_000600

Molecular Weight: 10.8 kDa (93aa), confirmed by MALDI-TOF.

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling