PPIF Protein (AA 30-207)

Catalog No. ABIN666719

Product Details

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Protein Type: Recombinant

Protein Characteristics: AA 30-207

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Characteristics: Cyclophilin F (PPIF), 30-207aa, Human,Recombinant, E.coli

Purity: > 95 % by SDS PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5, 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Alternative Name: Cyclophilin F (PPIF) (PPIF Products)

Background: Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. Recombinant PPIF protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Peptidylprolyl isomerase F, CYP3, Cyp-D, PPIF, Peptidylprolyl isomerase F Cyclophilin 3, Cyclophilin D, Cyclophilin F, Cyp D, CYP3, CypD, hCyP3, Peptidylprolyl isomerase F (cyclophilin F), Peptidyl prolyl cis trans isomerase, mitochondral, Peptidylprolyl isomerase F, PPIase, Rotamase. NCBI no.: NP_005720

Molecular Weight: 21 kDa (198aa), confirmed by MALDI-TOF.

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity