PTTG1 Protein (AA 1-202) (His tag)
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- Target See all PTTG1 Proteins
- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-202
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTTG1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PTTG1, 1-202 aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product PTTG1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl, 10% glycerol
- Storage
- 4 °C
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- Target
- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
- Alternative Name
- PTTG1 (PTTG1 Products)
- Synonyms
- EAP1 Protein, HPTTG Protein, PTTG Protein, TUTR1 Protein, PTTG1 Protein, securin Protein, AW555095 Protein, C87862 Protein, Pttg Protein, Pttg3 Protein, Securin Protein, Protein Cut2 Protein, pituitary tumor-transforming 1 Protein, pituitary tumor-transforming gene 1 Protein, securin, sister chromatid separation inhibitor Protein, PTTG1 Protein, Pttg1 Protein, cut2 Protein
- Background
- PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles, the first one is to help the transport of separase(cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: EAP1, HPTTG, PTTG, TUTR1, SECURIN, Pituitary tumor-transforming protein 1 ESP1 ASSOCIATED PROTEIN 1, Esp1-associated protein, MGC126883, MGC138276, Pds1, PTTG1 protein, PTTG1, Pituitary tumor transforming 1, PTTG 1, EAP 1, Cut2, Pituitary tumor transforming protein 1, AW555095, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor-transforming 1, isoform CRA_b, hPTTG, Pituitary tumor-transforming gene 1, TUTR 1, Pttg3, Pituitary tumor-transforming gene 1 protein, C87862, TUMOR TRANSFORMING 1, Tumor transforming protein 1,. NCBI no.: NP_004210
- Molecular Weight
- 24.1 kDa (222aa), confirmed by MALDI-TOF.
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