IL-22 Protein (AA 34-179) (His tag)
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- Target See all IL-22 (IL22) Proteins
- IL-22 (IL22) (Interleukin 22 (IL22))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 34-179
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-22 protein is labelled with His tag.
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL22 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- IL-22 (IL22) (Interleukin 22 (IL22))
- Alternative Name
- IL-22 (IL22 Products)
- Synonyms
- IL-21 Protein, IL-22 Protein, IL-D110 Protein, IL-TIF Protein, ILTIF Protein, TIFIL-23 Protein, TIFa Protein, zcyto18 Protein, IL-22a Protein, ILTIFa Protein, Iltif Protein, RGD1561292 Protein, interleukin-22 Protein, interleukin 22 Protein, IL22 Protein, il22 Protein, Il22 Protein
- Background
- Interleukin-22 (IL22) is also known as cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor (IL-TIF), which is belongs to the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.
- Molecular Weight
- 18.6 kDa
- NCBI Accession
- NP_065386
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