Biglycan Protein (BGN) (AA 38-368) (His tag)
BGN
Origin: Human
Host: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
Active
-
- Target See all Biglycan (BGN) Proteins
- Biglycan (BGN)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 38-368
-
Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Biglycan protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPDEEASGA DTSGVLDPDS VTPTYSAMCP FGCHCHLRVV QCSDLGLKSV PKEISPDTTL LDLQNNDISE LRKDDFKGLQ HLYALVLVNN KISKIHEKAF SPLRKLQKLY ISKNHLVEIP PNLPSSLVEL RIHDNRIRKV PKGVFSGLRN MNCIEMGGNP LENSGFEPGA FDGLKLNYLR ISEAKLTGIP KDLPETLNEL HLDHNKIQAI ELEDLLRYSK LYRLGLGHNQ IRMIENGSLS FLPTLRELHL DNNKLARVPS GLPDLKLLQV VYLHSNNITK VGVNDFCPMG FGVKRAYYNG ISLFNNPVPY WEVQPATFRC VTDRLAIQFG NYKKHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Measured in inhibit the cell growth using 3T3-L1 mouse embryonic fibroblast adipose-like cells. The ED50 for this effect is less or equal to 20 ug/ml.
- Top Product
- Discover our top product BGN Protein
-
Biglycan (BGN) (AA 1-368) protein (GST tag)
BGN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Biglycan (BGN) protein (Fc Tag)BGN Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Bioactivity Validated
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- Biglycan (BGN)
- Alternative Name
- BGN (BGN Products)
- Synonyms
- DSPG1 Protein, PG-S1 Protein, PGI Protein, SLRR1A Protein, BG Protein, BSPG1 Protein, bgn Protein, zgc:91989 Protein, dspg1 Protein, pg-s1 Protein, slrr1a Protein, xbgn Protein, BGN Protein, zgc:77123 Protein, DKFZp468I2427 Protein, biglycan Protein, biglycan L homeolog Protein, biglycan a Protein, biglycan S homeolog Protein, biglycan b Protein, BGN Protein, Bgn Protein, bgn.L Protein, bgna Protein, bgn.S Protein, bgn Protein, bgnb Protein
- Background
- BGN, also known as biglycan preproprotein, is a small leucine-rich repeat proteoglycan (SLRP). It plays an important role in the development and maintenance of many tissues. Core protein of this protein binds to the growth factors BMP-4 and influences its bioactivity. This protein is also involved in collagen fiber assembly. Recombinant human BGN protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 38.3kDa (340aa) 40-57KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001702
- UniProt
- P21810
- Pathways
- Glycosaminoglycan Metabolic Process
-
You are here:
