Integrin beta 4 Protein (ITGB4) (AA 28-710) (His tag)
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- Target See all Integrin beta 4 (ITGB4) Proteins
- Integrin beta 4 (ITGB4)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-710
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Integrin beta 4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPRVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPRHHHH HH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product ITGB4 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 6.8) containing 50 % glycerol, 1 mM DTT, 1 mM EDTA, 0.1M NaCl
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Integrin beta 4 (ITGB4)
- Alternative Name
- ITGB4 (ITGB4 Products)
- Synonyms
- AA407042 Protein, C230078O20 Protein, CD104 Protein, integrin subunit beta 4 Protein, integrin beta 4 Protein, ITGB4 Protein, Itgb4 Protein
- Background
- CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 14.1kDa (122aa) 13.5-18kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_932170
- UniProt
- P20963
- Pathways
- Integrin Complex
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