LCP2 Protein (AA 1-533) (His tag)
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- Target See all LCP2 Proteins
- LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-533
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This LCP2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPMALRNVP FRSEVLGWDP DSLADYFKKL NYKDCEKAVK KYHIDGARFL NLTENDIQKF PKLRVPILSK LSQEINKNEE RRSIFTRKPQ VPRFPEETES HEEDNGGWSS FEEDDYESPN DDQDGEDDGD YESPNEEEEA PVEDDADYEP PPSNDEEALQ NSILPAKPFP NSNSMYIDRP PSGKTPQQPP VPPQRPMAAL PPPPAGRNHS PLPPPQTNHE EPSRSRNHKT AKLPAPSIDR STKPPLDRSL APFDREPFTL GKKPPFSDKP SIPAGRSLGE HLPKIQKPPL PPTTERHERS SPLPGKKPPV PKHGWGPDRR ENDEDDVHQR PLPQPALLPM SSNTFPSRST KPSPMNPLPS SHMPGAFSES NSSFPQSASL PPYFSQGPSN RPPIRAEGRN FPLPLPNKPR PPSPAEEENS LNEEWYVSYI TRPEAEAALR KINQDGTFLV RDSSKKTTTN PYVLMVLYKD KVYNIQIRYQ KESQVYLLGT GLRGKEDFLS VSDIIDYFRK MPLLLIDGKN RGSRYQCTLT HAAGYPHHHH HH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product LCP2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
- Alternative Name
- LCP2 (LCP2 Products)
- Synonyms
- AI323664 Protein, BB161688 Protein, SLP-76 Protein, SLP76 Protein, twm Protein, Slp76 Protein, lymphocyte cytosolic protein 2 Protein, Lcp2 Protein, LCP2 Protein
- Background
- LCP2, also known as lymphocyte cytosolic protein 2, is an intracellular docking protein with a single SH2 recognition domain. It is involved in T-cell antigen receptor mediated signaling. This protein is phosphorylated by ZAP70 leading to NF-AT and IL2 gene activation. Recombinant human LCP2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 61.2kDa (542aa) 70-100KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_005556
- UniProt
- Q13094
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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