FCER2 Protein (AA 48-321) (His tag)
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- Target See all FCER2 Proteins
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 48-321
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This FCER2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPDTTQSLK QLEERAARNV SQVSKNLESH HGDQMAQKSQ STQISQELEE LRAEQQRLKS QDLELSWNLN GLQADLSSFK SQELNERNEA SDLLERLREE VTKLRMELQV SSGFVCNTCP EKWINFQRKC YYFGKGTKQW VHARYACDDM EGQLVSIHSP EEQDFLTKHA SHTGSWIGLR NLDLKGEFIW VDGSHVDYSN WAPGEPTSRS QGEDCVMMRG SGRWNDAFCD RKLGAWVCDR LATCTPPASE GSAESMGPDS RPDPDGRLPT PSAPLHSHHH HHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product FCER2 Protein
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Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (His tag)
FCER2 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) protein (His tag)FCER2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) protein (GST tag)FCER2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (His tag)FCER2 Origin: Mouse Host: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (Fc Tag)FCER2 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) (Active) protein (His tag,AVI tag,Biotin)FCER2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (Transcript Variant 1) (Active) proteinFCER2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- Alternative Name
- FCER2 (FCER2 Products)
- Synonyms
- BLAST-2 Protein, CD23 Protein, CD23A Protein, CLEC4J Protein, FCE2 Protein, IGEBF Protein, Fcer2a Protein, Fc fragment of IgE receptor II Protein, FCER2 Protein, Fcer2 Protein
- Background
- FCER2, also known as low affinity immunoglobulin epsilon Fc receptor isoform a, is a member of subgroup II of the C-type (Ca++-dependent) lectin superfamily. It is a low affinity receptor for B cell specific antigen and IgE. It plays an essential role in the growth and differentiation of B cells, and in the regulation of IgE production. This protein also exists in a soluble secretion form and functions as a powerful cleavage-promoting growth factor. Increased levels of soluble CD23 / FCER2 lead to the recruitment of unaffected B cells in the presentation of antigen peptides to allergen-specific B cells. Recombinant human FCER2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 32.0kDa (283aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_001993
- UniProt
- P06734
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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