Relaxin 2 Protein (RLN2) (AA 25-185) (His tag)
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- Target See all Relaxin 2 (RLN2) Proteins
- Relaxin 2 (RLN2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-185
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Relaxin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product RLN2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Relaxin 2 (RLN2)
- Alternative Name
- RLN2 (RLN2 Products)
- Synonyms
- H2 Protein, H2-RLX Protein, RLXH2 Protein, bA12D24.1.1 Protein, bA12D24.1.2 Protein, RFLX Protein, rln2 Protein, rln3c Protein, rlx3c Protein, si:rp71-39b20.5 Protein, relaxin 2 Protein, insulin-like 3 (Leydig cell) Protein, RLN2 Protein, insl3 Protein
- Background
- RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. It is 18 kDa in size and 185 aa in length. It contains a 24 aa signal sequence, a 3.3 kDa, 29 aa B domain, a 106 aa C (or connecting) domain, and a C-terminal, 2.7 kDa, 24 aa A domain. Recombinant human RLN2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 19.3kDa (170aa) 18-28kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_604390
- UniProt
- P04090
- Pathways
- Hormone Activity
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