HDAC8 Protein (AA 1-377) (His tag)
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- Target See all HDAC8 Proteins
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-377
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This HDAC8 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MEMPEEPANS GHSLPPVYIY SPEYVSICDS LVKVPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDEDH PDSIEYGLGY DCPATEGIFD YAAAIGGGTI TAAQCLIDGK CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFD RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDMSDVGLG KGRYYSVNVP IQDGIQDEKY YHICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY VLQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVVHHH HHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product HDAC8 Protein
-
Histone Deacetylase 8 (HDAC8) (AA 1-100) protein (GST tag)
HDAC8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Histone Deacetylase 8 (HDAC8) (AA 1-377) protein (GST tag)HDAC8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Histone Deacetylase 8 (HDAC8) protein (His tag)HDAC8 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
Histone Deacetylase 8 (HDAC8) (AA 1-377), (full length) protein (His-SUMO Tag)HDAC8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Alternative Name
- Hdac8 (HDAC8 Products)
- Synonyms
- HD8 Protein, CDLS5 Protein, HDACL1 Protein, MRXS6 Protein, RPD3 Protein, WTS Protein, 2610007D20Rik Protein, RGD1562895 Protein, wu:fd19a02 Protein, zgc:66196 Protein, ATHDA8 Protein, HDA8 Protein, HISTONE DEACETYLASE 8 Protein, T27G7.14 Protein, T27G7_14 Protein, histone deacetylase 8 Protein, histone deacetylase 8 Protein, histone deacetylase 8 L homeolog Protein, CC1G_05302 Protein, hdac8 Protein, HDAC8 Protein, Hdac8 Protein, hdac8.L Protein, HDA08 Protein
- Background
- Hdac8, also known as histone deacetylase 8 isoform 1, is a member of the class I Histone Deacetylases. Its specific inhibition reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. It expressed in the renal epithelial cells of the mouse kidney. Its activity contributes to renal protection and functional recovery and is required for renal regeneration after AKI. Recombinant mouse Hdac8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 42.5kDa (383aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_081658
- UniProt
- Q8VH37
- Pathways
- Cellular Glucan Metabolic Process
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