ACP5 Protein (AA 22-325)
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- Target See all ACP5 Proteins
- ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-325
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Application
- SDS-PAGE (SDS)
- Sequence
- ATPALRFVAV GDWGGVPNAP FHTAREMANA KEIARTVQIL GADFILSLGD NFYFTGVQDI NDKRFQETFE DVFSDRSLRK VPWYVLAGNH DHLGNVSAQI AYSKISKRWN FPSPFYRLHF KIPQTNVSVA IFMLDTVTLC GNSDDFLSQQ PERPRDVKLA RTQLSWLKKQ LAAAREDYVL VAGHYPVWSI AEHGPTHCLV KQLRPLLATY GVTAYLCGHD HNLQYLQDEN GVGYVLSGAG NFMDPSKRHQ RKVPNGYLRF HYGTEDSLGG FAYVEISSKE MTVTYIEASG KSLFKTRLPR RARP
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is >10,000 units/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmoles of p-nitrophenyl phosphate (pNPP) per minute at pH 5.0 at 37C
- Top Product
- Discover our top product ACP5 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))
- Alternative Name
- ACP5 (ACP5 Products)
- Background
- ACP5, also known as tartrate-resistant acid phosphatase type 5, is involved in osteopontin and bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias. Recombinant human ACP5 was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 34.3kDa (304aa) 28-40KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001104505
- UniProt
- P13686
- Pathways
- Transition Metal Ion Homeostasis
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