UBA2 Protein (AA 1-640) (His tag)

Catalog No. ABIN6387816

Product Details

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Protein Type: Recombinant

Protein Characteristics: AA 1-640

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This UBA2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: ADLMALSRGL PRELAEAVAG GRVLVVGAGG IGCELLKNLV LTGFSHIDLI DLDTIDVSNL NRQFLFQKKH VGRSKAQVAK ESVLQFYPKA NIVAYHDSIM NPDYNVEFFR QFILVMNALD NRAARNHVNR MCLAADVPLI ESGTAGYLGQ VTTIKKGVTE CYECHPKPTQ RTFPGCTIRN TPSEPIHCIV WAKYLFNQLF GEEDADQEVS PDRADPEAAW EPTEAEARAR ASNEDGDIKR ISTKEWAKST GYDPVKLFTK LFKDDIRYLL TMDKLWRKRK PPVPLDWAEV QSQGEETNAS DQQNEPQLGL KDQQVLDVKS YARLFSKSIE TLRVHLAEKG DGAELIWDKD DPSAMDFVTS AANLRMHIFS MNMKSRFDIK SMAGNIIPAI ATTNAVIAGL IVLEGLKILS GKIDQCRTIF LNKQPNPRKK LLVPCALDPP NPNCYVCASK PEVTVRLNVH KVTVLTLQDK IVKEKFAMVA PDVQIEDGKG TILISSEEGE TEANNHKKLS EFGIRNGSRL QADDFLQDYT LLINILHSED LGKDVEFEVV GDAPEKVGPK QAEDAAKSIT NGSDDGAQPS TSTAQEQDDV LIVDSDEEDS SNNADVSEEE RSRKRKLDEK ENLSAKRSRI EQKEELDDVI ALDHHHHHH

Purity: > 85 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Alternative Name: UBA2 (UBA2 Products)

Synonyms: ATSAE2 Protein, EMB2764 Protein, EMBRYO DEFECTIVE 2764 Protein, F3K23.23 Protein, F3K23_23 Protein, SUMO-ACTIVATING ENZYME 2 Protein, SUMO-activating enzyme 2 Protein, ARX Protein, SAE2 Protein, AA986091 Protein, Arx Protein, Sae2 Protein, UBA1 Protein, Ubl1a2 Protein, Uble1b Protein, sae2 Protein, sae2-B Protein, uba2-a Protein, uba2-b Protein, uble1b-B Protein, sae2b Protein, uble1b Protein, wu:fi17g06 Protein, zgc:66354 Protein, SUMO1 activating enzyme subunit 2 Protein, SUMO-activating enzyme 2 Protein, ubiquitin like modifier activating enzyme 2 Protein, ubiquitin-like modifier activating enzyme 2 Protein, ubiquitin like modifier activating enzyme 2 L homeolog Protein, MICPUN_63834 Protein, MICPUCDRAFT_36729 Protein, SAE2 Protein, UBA2 Protein, Uba2 Protein, uba2.L Protein, uba2 Protein

Background: UBA2, also known as SUMO-activating enzyme subunit 2, is a family of small and related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. It is conjugated to a variety of molecules in the presence of the SAE1/UBA2 SUMO-activating(E1) enzyme and the UBE2I/Ubc9 SUMO-conjugating(E2) enzyme. It may represent an important mechanism to protect neurons during episodes of cerebral ischemia. Recombinant human UBA2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 72.3kDa (649aa) 70-100kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_005490

UniProt: Q9UBT2