SORD Protein (AA 1-357)

Catalog No. ABIN7281100

Product Details

Target: SORD (Sorbitol Dehydrogenase (SORD))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 1-357

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP

Purity: > 90 % by SDS - PAGE

Biological Activity Comment: Specific activity is > 15 units/mg, and is defined as the amount of enzyme that catalyze the reduction 1.0 umole of D-fructose to D-sorbitol per minute at pH 7.5 at 37C.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Bioactivity Validated

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer(  pH 8.5) containing 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD (SORD Products)

Synonyms: SORD1 Protein, Sdh-1 Protein, Sdh1 Protein, Sodh-1 Protein, SDH Protein, sord Protein, MGC83437 Protein, BmSDH Protein, PSPTO0363 Protein, SODH-1 Protein, RATSDHE1 Protein, SDH2 Protein, Sdh Protein, Sdhe1 Protein, TDH Protein, 4733401P19Rik Protein, AI836084 Protein, CGI-97 Protein, SDS Protein, zgc:63674 Protein, sorbitol dehydrogenase Protein, sorbitol dehydrogenase L homeolog Protein, Sorbitol dehydrogenase Protein, serine dehydratase Protein, SBDS ribosome maturation factor Protein, SORD Protein, Sord Protein, sord.L Protein, sord Protein, Sdh Protein, LOC733025 Protein, polS Protein, RS_RS10765 Protein, sdh Protein, smoS Protein, Rsph17029_1731 Protein, Srd Protein, RSKD131_1411 Protein, SDS Protein, Sds Protein, Sbds Protein

Background: SORD, also known as sorbitol dehydrogenase, is a member of the zinc-containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney and in the lens of the eye. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses. Recombinant human SORD protein, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 38.3kDa (357aa)

NCBI Accession: NP_003095