Kallikrein 13 Protein (AA 17-277) (His tag)
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- Target See all Kallikrein 13 (KLK13) Proteins
- Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 17-277
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Kallikrein 13 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GGVSQESSKV LNTNGTSGFL PGGYTCFPHS QPWQAALLVQ GRLLCGGVLV HPKWVLTAAH CLKEGLKVYL GKHALGRVEA GEQVREVVHS IPHPEYRRSP THLNHDHDIM LLELQSPVQL TGYIQTLPLS HNNRLTPGTT CRVSGWGTTT SPQVNYPKTL QCANIQLRSD EECRQVYPGK ITDNMLCAGT KEGGKDSCEG DSGGPLVCNR TLYGIVSWGD FPCGQPDRPG VYTRVSRYVL WIRETIRKYE TQQQKWLKGP QHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is > 8,000 pmol/min/ug. One unit will hydrolyze 1.0 pmole of BAEE to Na-Benzoyl-L-arginine per minute at pH8.0 at 25C.
- Top Product
- Discover our top product KLK13 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))
- Alternative Name
- KLK13 (KLK13 Products)
- Synonyms
- KLK-L4 Protein, KLKL4 Protein, Egfbp-2 Protein, mGk-13 Protein, kallikrein related peptidase 13 Protein, kallikrein related-peptidase 13 Protein, KLK13 Protein, Klk13 Protein
- Background
- KLK13, also known as kallikrein-13, belongs to Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK13 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. Recombinant human KLK13, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.7kDa (267aa) 28-40KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_056411
- UniProt
- Q9UKR3
- Pathways
- Complement System
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