MMP13 Protein (AA 104-471) (His tag)
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- Target See all MMP13 Proteins
- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 104-471
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MMP13 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSYNVFPRT LKWSKMNLTY RIVNYTPDMT HSEVEKAFKK AFKVWSDVTP LNFTRLHDGI ADIMISFGIK EHGDFYPFDG PSGLLAHAFP PGPNYGGDAH FDDDETWTSS SKGYNLFLVA AHEFGHSLGL DHSKDPGALM FPIYTYTGKS HFMLPDDDVQ GIQSLYGPGD EDPNPKHPKT PDKCDPSLSL DAITSLRGET MIFKDRFFWR LHPQQVDAEL FLTKSFWPEL PNRIDAAYEH PSHDLIFIFR GRKFWALNGY DILEGYPKKI SELGLPKEVK KISAAVHFED TGKTLLFSGN QVWRYDDTNH IMDKDYPRLI EEDFPGIGDK VDAVYEKNGY IYFFNGPIQF EYSIWSNRIV RVMPANSILW C
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product MMP13 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.15M NaCl, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
- Alternative Name
- MMP13 (MMP13 Products)
- Synonyms
- CLG3 Protein, MANDP1 Protein, Clg Protein, MMP-13 Protein, Mmp1 Protein, cb1034 Protein, mmp13 Protein, gene A Protein, xCol Protein, xcl3 Protein, MMP13 Protein, MGC108008 Protein, matrix metallopeptidase 13 Protein, matrix metallopeptidase 13a Protein, matrix metallopeptidase 13 (collagenase 3) like S homeolog Protein, matrix metallopeptidase 13 (collagenase 3) Protein, matrix metalloproteinase 13 Protein, matrix metallopeptidase 13 (collagenase 3) like L homeolog Protein, MMP13 Protein, Mmp13 Protein, mmp13a Protein, mmp13l.S Protein, mmp13 Protein, LOC100136348 Protein, mmp13l.L Protein
- Background
- MMP13 of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Recombinant human MMP13 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 44.7 kDa (391aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_002418
- UniProt
- P45452
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