THG1L Protein (His tag)
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- Target See all THG1L Proteins
- THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This THG1L protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product THG1L Protein
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- Comment
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Synonyms: Probable tRNA (His) guanylyltransferase, ICF45
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
- Alternative Name
- THG1L (THG1L Products)
- Synonyms
- ICF45 Protein, IHG-1 Protein, 1700121M19Rik Protein, 5730409G07Rik Protein, AA387658 Protein, tRNA-histidine guanylyltransferase 1 like Protein, tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Protein, tRNA-histidine guanylyltransferase 1-like Protein, THG1L Protein, Thg1l Protein
- Background
- Probable tRNA (His) guanylyltransferase, also known as THG1L, belongs to the tRNA (His) gyanylytransferase family. Localized to the cytoplasm, THG1L is also found near the nuclear membrane and is expressed in many tissues, including liver and lung. Upon DNA damage, THG1L is phosphorylated, most likely by ATM or ATR. It is expressed in a cell cycle-dependent manner and may be involved in cell cycle progression and cell proliferation. Recombinant human THG1L protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 34 kDa (292aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_060342
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