MUTED Protein (His tag)
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- Target See all MUTED Proteins
- MUTED (Muted Homolog (MUTED))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MUTED protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MUTED Protein
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- Comment
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Synonyms: Muted homolog, MU
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 40% glycerol, 2 mM DTT, 0.1 MM PMSF, 1 MM EDTA
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- MUTED (Muted Homolog (MUTED))
- Alternative Name
- MUTED (MUTED Products)
- Synonyms
- BLOS5 Protein, MU Protein, MUTED Protein, muted Protein, 1810074A19Rik Protein, Muted Protein, mu Protein, biogenesis of lysosomal organelles complex 1 subunit 5 Protein, biogenesis of lysosomal organelles complex 1 subunit 5 L homeolog Protein, biogenesis of lysosomal organelles complex-1, subunit 5, muted Protein, BLOC1S5 Protein, bloc1s5.L Protein, Bloc1s5 Protein
- Background
- Muted homolog, also known as MUTED, is involved in the development of lysosome related organelles, such as melanosomes and platelet dense granules. MUTED interacts with pallidin, dystrobrevin binding protein 1 and CNO/cappuccino. It is part of the biogenesis of lysosome related organelles complex 1 (BLOC1). Also, MUTED is ubiquitously expressed with higher levels in brain, bone marrow, kidney, and liver and lower levels in skeletal muscle. Recombinant human MUTED protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 24 kDa (210aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_958437
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