ARHGDIB Protein (GST tag)
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- Target See all ARHGDIB Proteins
- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ARHGDIB protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ARHGDIB Protein
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- Comment
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Synonyms: Rho GDP-dissociation inhibitor 2, D4, GDIA2, GDID4, Ly-GDI, LYGDI, RAP1GN1, RhoGDI2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- phosphate-buffered Saline(pH 7.4) containing 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
- Alternative Name
- ARHGDIB (ARHGDIB Products)
- Synonyms
- ARHGDIB Protein, zgc:65966 Protein, arhgdib Protein, MGC69067 Protein, gdia2 Protein, rhodgi-2 Protein, rhodgi2 Protein, D4 Protein, GDIA2 Protein, GDID4 Protein, LYGDI Protein, Ly-GDI Protein, RAP1GN1 Protein, RhoGDI2 Protein, Gdid4 Protein, Rho GDP dissociation inhibitor (GDI) gamma Protein, Rho GDP dissociation inhibitor (GDI) beta S homeolog Protein, Rho GDP dissociation inhibitor beta Protein, Rho GDP dissociation inhibitor (GDI) beta Protein, Rho, GDP dissociation inhibitor (GDI) beta Protein, arhgdig Protein, arhgdib.S Protein, ARHGDIB Protein, arhgdib Protein, Arhgdib Protein
- Background
- Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. Recombinant human ARHGDIB protein, fused to GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 49.4 kDa (428aa)
- NCBI Accession
- NP_001166
- Pathways
- Caspase Cascade in Apoptosis
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