TDO2 Protein (AA 1-406) (His tag)
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- Target See all TDO2 Proteins
- TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-406
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TDO2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TDO2, 1-406aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TDO2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
- Storage
- 4 °C
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- Target
- TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
- Alternative Name
- TDO2 (TDO2 Products)
- Synonyms
- Tdo2 Protein, tdo2l Protein, fi30d08 Protein, zgc:63488 Protein, wu:fi30d08 Protein, TDO2 Protein, fb62b10 Protein, tdo2 Protein, wu:fb62b10 Protein, zgc:103693 Protein, DDBDRAFT_0190495 Protein, DDBDRAFT_0231363 Protein, DDB_0190495 Protein, DDB_0231363 Protein, TDO Protein, TO Protein, TPH2 Protein, TRPO Protein, AA407491 Protein, chky Protein, Tdo Protein, tryptophan 2,3-dioxygenase b Protein, tryptophan 2,3-dioxygenase Protein, tryptophan 2,3-dioxygenase a Protein, tryptophan 2,3-dioxygenase L homeolog Protein, tdo2b Protein, tdo2 Protein, TDO2 Protein, MADE_02822 Protein, CtCNB1_3657 Protein, tdo2a Protein, CNC04830 Protein, tdo Protein, Mrub_2119 Protein, Deipr_2235 Protein, Acav_1166 Protein, Mesop_4278 Protein, Tdo2 Protein, tdo2.L Protein
- Background
- TDO2, also known as TDO, is a ferrous heme enzyme that catalyzes the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. It incorporates oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Recombinant human TDO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Tryptophan 2,3-dioxygenase, TDO, TPH2, TRPO. NCBI no.: NP_005642
- Molecular Weight
- 50.0 kDa (426aa), confirmed by MALDI-TOF
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