CENPA Protein (His tag)
-
- Target See all CENPA Proteins
- CENPA (Centromere Protein A (CENPA))
- Protein Type
- Recombinant
-
Origin
- Human
- Host
- Please inquire
- Purification tag / Conjugate
- This CENPA protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Characteristics
- Recombinant Human Centromere Protein-A
- Purity
- > 90 % as determined by SDS-PAGE.
- Top Product
- Discover our top product CENPA Protein
-
Centromere Protein A (CENPA) (AA 1-114) protein (GST tag)
CENPA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Centromere Protein A (CENPA) (AA 1-134), (full length) protein (His tag)CENPA Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Centromere Protein A (CENPA) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CENPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Centromere Protein A (CENPA) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CENPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Western-Blot with monoclonal anti-hexa-His-tag antibody and Scleroderma patient sera. 0.15-0.4 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for biotinylation and iodination.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- CENPA is supplied in 20mM HEPES buffer pH-8, 100mM sodium chloride, and 6M Urea. Immunological functions 1. Binds IgG-type human auto-antibodies. 2. Standard ELISA test (checker-board analysis of positive/negative sera panels including CDC international reference sera).
- Storage
- 4 °C
-
- Target
- CENPA (Centromere Protein A (CENPA))
- Alternative Name
- Centromere Protein-A (CENPA Products)
- Synonyms
- CENP-A Protein, CenH3 Protein, Cenp-A Protein, cenpx Protein, cenp-a Protein, sim2 Protein, Cenp-a Protein, RGD1563607 Protein, CENPA Protein, centromere protein A Protein, centromere protein-A Protein, centromeric histone-3 like protein Protein, centromere-specific histone H3 CENP-A Protein, cenp-A Protein, centromere protein A L homeolog Protein, histone H3-like centromeric protein A Protein, CENPA Protein, Cenpa Protein, CENP-A Protein, cenpa Protein, cenp-A Protein, cnp1 Protein, HAN_3g422 Protein, Cenp-a Protein, cenpa.L Protein, CMU_016480 Protein
- Background
- CENPA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 17,015 Dalton. CENPA is expressed with a -6x His tag and purified by proprietary chromatographic techniques. Introduction: Centromere proteins are a group of proteins which form and/or mediate the function of centromeres, the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently, 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies, the anti-centromere antibodies. CENPA is another important centromeric autoantigen in addition to CENPB: it has a molecular weight of approx. 20 kDa and is incorporated into centromeric chromatin due to its histone-like properties. CENPA antibodies are an important marker for correct diagnosis of Scleroderma / CREST syndrome in CENPB-autoantibody negative patients. Synonyms: Histone H3-like centromeric protein A, Centromere protein A, CENP-A, Centromere autoantigen A, CENPA.
- Pathways
- Chromatin Binding, Maintenance of Protein Location
-
