CD84 Protein (CD84) (AA 22-225) (His tag,AVI tag,Biotin)

Catalog No. ABIN5955008

Product Details

Target: CD84

Protein Type: Recombinant

Protein Characteristics: AA 22-225

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD84 protein is labelled with His tag,AVI tag,Biotin.

Sequence: AA 22-225

Specificity: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Comment:

Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: CD84

Alternative Name: CD84 (CD84 Products)

Synonyms: RGD1564553 Protein, A130013D22Rik Protein, CDw84 Protein, SLAMF5 Protein, LY9B Protein, hCD84 Protein, mCD84 Protein, CD84 molecule Protein, CD84 antigen Protein, Cd84 Protein, CD84 Protein

Background: Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily. CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain. CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering. CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.

Molecular Weight: 26.5 kDa

NCBI Accession: NP_003865