Ephrin B1 Protein (EFNB1) (AA 28-237) (hIgG-His-tag)

Catalog No. ABIN7281363

Product Details

Target: Ephrin B1 (EFNB1)

Protein Type: Recombinant

Protein Characteristics: AA 28-237

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This Ephrin B1 protein is labelled with hIgG-His-tag.

Application: SDS-PAGE (SDS)

Sequence: ADPLAKNLEP VSWSSLNPKF LSGKGLVIYP KIGDKLDIIC PRAEAGRPYE YYKLYLVRPE QAAACSTVLD PNVLVTCNRP EQEIRFTIKF QEFSPNYMGL EFKKHHDYYI TSTSNGSLEG LENREGGVCR TRTMKIIMKV GQDPNAVTPE QLTTSRPSKE ADNTVKMATQ APGSRGSLGD SDGKHETVNQ EEKSGPGASG GSSGDPDGFF NSKLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH

Purity: > 90 % by SDS - PAGE

Endotoxin Level: < 0.1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Ephrin B1 (EFNB1)

Alternative Name: EFNB1 (EFNB1 Products)

Synonyms: EFNB1 Protein, LERK2 Protein, Cek5-L Protein, EFL-3 Protein, Elk-L Protein, Epl2 Protein, Eplg2 Protein, LERK-2 Protein, Lerk2 Protein, Stra1 Protein, CFND Protein, CFNS Protein, EFL3 Protein, EPLG2 Protein, cfnd Protein, cfns Protein, efl3 Protein, efnb1-A Protein, ephrinB1 Protein, eplg2 Protein, lerk2 Protein, ephrin B1 Protein, ephrin-B1 Protein, ephrin-B1 L homeolog Protein, EFNB1 Protein, Efnb1 Protein, efnb1 Protein, efnb1.L Protein

Background: EFNB1, also known as ephrin-B1, is a member of Eph family. It binds to the receptor tyrosine kinases EPHB1 and EPHA1. This protein also binds Eph receptors residing on adjacent cells which affect signaling to neighboring cells. It plays a role in cellular migration, axon guidance, osteoclast differentiation and function, cardiac muscle morphogenesis, and tumorigenesis. Recombinant human EFNB1 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 50.3kDa (452aa) 50-70KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_004420

UniProt: P98172

Pathways: RTK Signaling