Peroxiredoxin 5 Protein (PRDX5) (AA 53-214)
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- Target See all Peroxiredoxin 5 (PRDX5) Proteins
- Peroxiredoxin 5 (PRDX5)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 53-214
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL
- Purity
- > 95 % by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is >9,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for 1minute.
- Top Product
- Discover our top product PRDX5 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM HEPES ( pH 7.4)
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Peroxiredoxin 5 (PRDX5)
- Alternative Name
- PRDX5 (PRDX5 Products)
- Background
- Peroxiredoxin 5, also known as PRDX5, is a member of the peroxiredoxin family of antioxidant enzymes, which reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. This protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. It has been reported that PRDX5 is involved in intracellular redox signaling. Recombinant human PRDX5, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 17kDa (162aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_036226
- UniProt
- P30044
- Pathways
- Cell RedoxHomeostasis
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