BTLA Protein (AA 31-157) (His tag)
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- Target See all BTLA Proteins
- BTLA (B and T Lymphocyte Associated (BTLA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-157
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This BTLA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPKESCDVQ LYIKRQSEHS ILAGDPFELE CPVKYCANRP HVTWCKLNGT TCVKLEDRQT SWKEEKNISF FILHFEPVLP NDNGSYRCSA NFQSNLIESH STTLYVTDVK SASERPSKDE MASRPWLLYS HHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product BTLA Protein
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B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (Fc Tag)
BTLA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (His-Avi Tag)BTLA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (His-Avi Tag,Biotin)BTLA Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (mFc-His Tag)BTLA Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (His tag)BTLA Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
B and T Lymphocyte Associated (BTLA) (AA 30-176) protein (His tag)BTLA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
B and T Lymphocyte Associated (BTLA) protein (mFc Tag)BTLA Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
B and T Lymphocyte Associated (BTLA) (AA 30-176) protein (mFc Tag)BTLA Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
B and T Lymphocyte Associated (BTLA) (AA 190-289) protein (GST tag)BTLA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
B and T Lymphocyte Associated (BTLA) (Active) protein (Fc Tag)BTLA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Alternative Name
- BTLA (BTLA Products)
- Synonyms
- BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
- Background
- BTLA, also known as B- and T-lymphocyte attenuator isoform 1, is an inhibitory molecule which belongs to the Ig superfamily. It is a type 1 transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. This protein is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1(PD-1). Also, it is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses. Recombinant human BTLA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 15.7kDa (136aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_861445
- UniProt
- Q7Z6A9
- Pathways
- Cancer Immune Checkpoints
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